| Identification | Back Directory | [Name]
BML-259 | [CAS]
267654-00-2 | [Synonyms]
BML-259
CAY10554
2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide
Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- | [Molecular Formula]
C14H16N2OS | [MDL Number]
MFCD09802287 | [MOL File]
267654-00-2.mol | [Molecular Weight]
260.35 |
| Chemical Properties | Back Directory | [Melting point ]
150-152℃ | [storage temp. ]
RT | [solubility ]
Soluble in DMSO (up to 25 mg/ml). | [form ]
White solid. | [color ]
white | [Stability:]
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Hazard Information | Back Directory | [Description]
BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1 | [Uses]
BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively[1]. | [Definition]
ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides. | [storage]
Store at -20°C | [References]
1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521 |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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