| Identification | Back Directory | [Name]
2',3',5'-Tri-O-benzyl-4'-thio-arabinouridine | [CAS]
267665-69-0 | [Synonyms]
2',3',5'-Tri-O-benzyl-4'-thio-arabinouridine
1-(2',3',5'-Tri-O-benzyl-4'-thio-b-D-arabinofuranosyl)uracil
2,4(1H,3H)-Pyrimidinedione, 1-[2,3,5-tris-O-(phenylmethyl)-4-thio-β-D-arabinofuranosyl]- | [Molecular Formula]
C30H30N2O5S | [MDL Number]
MFCD30718560 | [MOL File]
267665-69-0.mol | [Molecular Weight]
530.64 |
| Hazard Information | Back Directory | [Uses]
2’,3’,5’-Tri-O-benzyl-4’-thio-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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