| Chemical Properties | Back Directory | [Boiling point ]
1276.1±65.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [solubility ]
DMSO : 100 mg/mL (105.49 mM; Need ultrasonic) | [form ]
Solid | [pka]
10.74±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
MC-VA-PAB-Exatecan is a agent-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity[1]. | [IC 50]
Camptothecins | [References]
[1] KRAIEM, et al. Treatment of cancer. WO2021151984A1. |
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