| Identification | Back Directory | [Name]
3,5-DibroMo-1-Methylpyridin-4(1H)-one | [CAS]
2683-35-4 | [Synonyms]
3,5-DibroMo-1-Methylpyridin-4(1H)-one
4(1H)-Pyridinone, 3,5-dibromo-1-methyl- | [Molecular Formula]
C6H5Br2NO | [MDL Number]
MFCD23135477 | [MOL File]
2683-35-4.mol | [Molecular Weight]
266.92 |
| Chemical Properties | Back Directory | [Melting point ]
193-194 °C | [Boiling point ]
253.7±40.0 °C(Predicted) | [density ]
2.130±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [pka]
-2.10±0.10(Predicted) | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
General method: Iodomethane (4 mmol, 2 eq.) was added to a solution of 3,5-dibromo-4-methoxypyridine (2 mmol) dissolved in different solvents (15 mL) and the mixture was refluxed overnight. The reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was purified by column chromatography (eluent ratio: ethyl acetate/methanol, 20:1→5:1) to afford the target product 3,5-dibromo-1-methylpyridin-4(1H)-one. | [References]
[1] Synthetic Communications, 2017, vol. 47, # 9, p. 872 - 877 |
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Cool Pharm, Ltd
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021-58581007 18019463053 |
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http://www.coolpharm.com.cn |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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