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268546-19-6

268546-19-6 Structure

268546-19-6 Structure
IdentificationBack Directory
[Name]

6H-1,3,6,8a-Tetraazaacenaphthylene, 6-(cyclopropylmethyl)-2-(2,4-dichlorophenyl)-7-ethyl-7,8-dihydro-4-methyl-, (7S)- (9CI)
[CAS]

268546-19-6
[Synonyms]

NBI-35965
6H-1,3,6,8a-Tetraazaacenaphthylene, 6-(cyclopropylmethyl)-2-(2,4-dichlorophenyl)-7-ethyl-7,8-dihydro-4-methyl-, (7S)- (9CI)
[Molecular Formula]

C21H22Cl2N4
[MOL File]

268546-19-6.mol
[Molecular Weight]

401.33
Chemical PropertiesBack Directory
[Boiling point ]

563.1±50.0 °C(Predicted)
[density ]

1.45±0.1 g/cm3(Predicted)
[pka]

7.91±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

NBI-35965 is an antagonist of corticotropin-releasing factor receptor 1 (CRF-R1). NBI-35965 can be used in nervous system related research[1].
[IC 50]

CRFR1
[References]

[1] Li C, et al. CRF-5-HT interactions in the dorsal raphe nucleus and motivation for stress-induced opioid reinstatement. Psychopharmacology (Berl). 2021 Jan;238(1):29-40. DOI:10.1007/s00213-020-05652-3
268546-19-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135 , +8613564774135
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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