| Identification | Back Directory | [Name]
3-aminopiperidine-2,6-dione hydrochloride | [CAS]
2686-86-4 | [Synonyms]
3-aminopiperidine-2
6-dione hydrochloride
3-AMinopiperidine-2,6-Dione-HCL
Glutamic acid imide-DL-hydrochloride
3-aminopiperidine-2,6-dione hydrochloride
3-aMino-aza-cyclohexane 2,6-dione hydrochloride
3-Aminopiperidine-2,6-dione hydrochloride (1:1)
(+-)-3-Amino-2,6-piperidinedione monohydrochloride
2,6-Piperidinedione, 3-amino-, monohydrochloride, (+-)-
5-butyl-3-(1-naphthalenyl)-2-sulfanylidene-4-thiazolidinone
3-Amino-2，6-piperidinedione hydrochloride 2686-86-4 2，6-dioxopiperidine-3-ammonium chloride | [EINECS(EC#)]
806-697-5 | [Molecular Formula]
C5H9ClN2O2 | [MDL Number]
MFCD11042437 | [MOL File]
2686-86-4.mol | [Molecular Weight]
164.59 |
| Chemical Properties | Back Directory | [Melting point ]
>208oC (dec.) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated) | [form ]
Solid | [color ]
Off-White |
| Hazard Information | Back Directory | [Description]
3-aminopiperidine-2,6-dione hydrochloride is an important organic synthetic raw material for the preparation of the antineoplastic agent pomalidomide, which is used to treat AIDS-related kaposi's sarcoma in patients who have not responded well to highly active antiretroviral therapy (HAART). It is also used to treat Kaposi's sarcoma in HIV-uninfected (HIV-negative) patients. | [Uses]
3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce?ubiquitination and degradation of CK1α in del(5q) MDS.?It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. |
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