| Identification | Back Directory | [Name]
N-(3,5-Dichlorobenzoyl)-5,5-dimethyl-L-norleucine | [CAS]
2691846-87-2 | [Synonyms]
SORT-PGRN interaction inhibitor 3
N-(3,5-Dichlorobenzoyl)-5,5-dimethyl-L-norleucine | [Molecular Formula]
C15H19Cl2NO3 | [MOL File]
2691846-87-2.mol | [Molecular Weight]
332.22 |
| Chemical Properties | Back Directory | [Boiling point ]
459.5±45.0 °C(Predicted) | [density ]
1.257±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
3.80±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
SORT-PGRN interaction inhibitor 3 (Compound 13) is a SORT-PGRN interaction inhibitor (IC50: 0.17 μM). SORT-PGRN interaction inhibitor 3 can be used for research of neurodegenerative diseases[1]. | [References]
[1] Stachel SJ, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403. DOI:10.1016/j.bmcl.2020.127403 |
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