| Identification | Back Directory | [Name]
2'-Azido-2'-deoxyuridine | [CAS]
26929-65-7 | [Synonyms]
N3-dU
N3dUrd
2'-Az-dU
2'-N3-2'-dU
2''-AZIDO-D-URIDINE
2'-AZIDO-2'-DEOXYURIDINE
Uridine,2'-azido-2'-deoxy-
2'-Azido-2'-deoxy-D-uridine
2'-AZIDO-2'-DEOXYURIDINE HPLC 98+%
2'-Azido-2'-deoxyuridine USP/EP/BP
1-[3-Azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione | [EINECS(EC#)]
248-113-6 | [Molecular Formula]
C9H11N5O5 | [MDL Number]
MFCD00043045 | [MOL File]
26929-65-7.mol | [Molecular Weight]
269.21 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1]. 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] Kang SH, et al. Biological activity and phosphorylation of 2'-azido-2'-deoxyuridine and 2'-azido-2'-deoxycytidine. Nucleosides Nucleotides. 1998 Jun;17(6):1077-88. DOI:10.1080/07328319808004221 |
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