2694866-10-7

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2694866-10-7 Structure

Identification	Back Directory
[Name] FOXM1-IN-2
[CAS] 2694866-10-7
[Synonyms] FOXM1-IN-2 Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-6-[4-[[19-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-2,18-dioxo-7,10,13-trioxa-3,17-diazanonadec-1-yl]oxy]phenyl]-N-(4-fluorophenyl)-4-(trifluoromethyl)-
[Molecular Formula] C48H47F4N7O12S
[MOL File] 2694866-10-7.mol
[Molecular Weight] 1021.99

Chemical Properties	Back Directory
[Boiling point ] 1156.282±65.00 °C(Press: 760.00 Torr)(predicted)
[density ] 1.438±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka] 10.242±0.70(predicted)

Hazard Information	Back Directory
[Uses] FOXM1-IN-2 is a FOXM1 inhibitor, with antineoplastic activity[1].
[References] [1] Luo G, et al. Targeting of the FOXM1 Oncoprotein by E3 Ligase-Assisted Degradation. J Med Chem. 2021 Dec 9;64(23):17098-17114. DOI:10.1021/acs.jmedchem.1c01069

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