| Identification | Back Directory | [Name]
7H-Dibenzo[de,h]quinolin-7-one, 5-[4-(2-methyl-1-piperidinyl)butoxy]- | [CAS]
2699090-78-1 | [Synonyms]
AChE-IN-7
7H-Dibenzo[de,h]quinolin-7-one, 5-[4-(2-methyl-1-piperidinyl)butoxy]- | [Molecular Formula]
C26H28N2O2 | [MOL File]
2699090-78-1.mol | [Molecular Weight]
400.51 |
| Hazard Information | Back Directory | [Uses]
AChE-IN-7 (Compound 16) is a selective and potent inhibitor of acetylcholinesterase (eeAChE IC50 = 0.045 μM; eeBuChE IC50 = 19.68 μM). AChE-IN-7 is safe in vivo and in vitro, and shows good overall pharmacokinetic performance and high bioavailability (F = 55.5%). AChE-IN-7 also has high BBB permeability[1]. |
|
|