| Chemical Properties | Back Directory | [Boiling point ]
297.798±3.00 °C(Press: 760.00 Torr)(predicted) | [density ]
0.829±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml |
| Hazard Information | Back Directory | [Description]
Hexadecanal-d5 is intended for use as an internal standard for the quantification of hexadecanal by GC- or LC-MS. Sphingosine-1-phosphate (S1P) is a potent bioactive phospholipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.1 Hexadecanal is the 16-carbon aldehyde analog of palmitic acid. It is produced from the irreversible cleavage of S1P by S1P lyase 1 and is a major component of plasmalogen.2,3 | [Uses]
Hexadecanal-d5 (Palmitaldehyde-d5) is deuterium labeled Hexadecanal. Hexadecanal (Palmitaldehyde) , a volatile long-chain aliphatic aldehyde, is emitted from human feces, skin, and breath. The receptor for hexadecanal(OR37B) is highly conserved across mammals. Hexadecanal may exert its effects by modulating functional connectivity between the brain substrates of social appraisal and the brain substrates of aggressive execution. Also, Hexadecanal is confirmed to be highly deterrent to the ant Lasius niger. Hexadecanal is promising for the research of startle responses and aggression[1][2][3][4] | [References]
1. Leclercq, T.M., and Pitson, S.M. Cellular signalling by sphingosine kinase and sphingosine 1-phosphate IUBMB Life 58(8),467-472(2006).
2. Reiss, U., Oskouian, B., Zhou, J., et al. Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis J. Biol. Chem. 279(2),1281-1290(2004).
3. Pyne, S., and Pyne, N.J. Sphingosine 1-phosphate signalling in mammalian cells Biochem. J. 349(Pt 2),385-402(2000). |
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