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2703915-71-1

2703915-71-1 Structure

2703915-71-1 Structure
IdentificationBack Directory
[Name]

4-Piperidinecarboxaldehyde, 1-[4-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-
[CAS]

2703915-71-1
[Synonyms]

1-(4-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)phenyl)piperidine-4-carbaldehyde
4-Piperidinecarboxaldehyde, 1-[4-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-
[Molecular Formula]

C16H19N3O3
[MOL File]

2703915-71-1.mol
[Molecular Weight]

301.34
Chemical PropertiesBack Directory
[density ]

1.312±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

13.02±0.20(Predicted)
[color ]

Off-white to light brown
Hazard InformationBack Directory
[Uses]

E3 ligase Ligand 51 is the ligand for E3 ligase VHL, that can be used for synthesis of PROTAC BTK Degrader-12 (HY-170413)[1].
[References]

[1] Wang H, et al., Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inhibitors with e3 ligase ligand and methods of use. WO2021219070
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