| Identification | Back Directory | [Name]
1-Propanone, 2-(4-chlorophenyl)-3-[(1-methylethyl)amino]-1-[3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]oct-8-yl]-, (2S)- | [CAS]
2709045-53-2 | [Synonyms]
AKT-IN-9
1-Propanone, 2-(4-chlorophenyl)-3-[(1-methylethyl)amino]-1-[3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]oct-8-yl]-, (2S)- | [Molecular Formula]
C24H29ClN6O | [MOL File]
2709045-53-2.mol | [Molecular Weight]
452.98 |
| Hazard Information | Back Directory | [Uses]
AKT-IN-9 is a potent inhibitor of AKT. Protein kinase B (PKB, also known as AKT) is central to PI3K/AKT/mTOR signaling in cells, and its function is important for cell growth, survival, differentiation and metabolism. AKT-IN-9 has the potential for the research of breast and prostate cancer (extracted from patent WO2021185238A1, compound 1)[1]. | [References]
[1] Xin Li, et al. Thickened dicyclic derivatives, their preparation methods and their application in medicine. Patent WO2021185238A1. |
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