| Identification | Back Directory | [Name]
Ethanesulfonamide, N-[6-[4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl]-3-pyridinyl]- | [CAS]
2711720-45-3 | [Synonyms]
HIF-PHD-IN-2
Ethanesulfonamide, N-[6-[4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl]-3-pyridinyl]- | [Molecular Formula]
C17H15N5O3S | [MOL File]
2711720-45-3.mol | [Molecular Weight]
369.4 |
| Hazard Information | Back Directory | [Uses]
HIF-PHD-IN-2 (compound 25) is a potent PHD inhibitor with IC50s of <100 nM for PHD1, PHD2 and PHD3, respectively[1]. | [References]
[1] Sabnis RW. Novel Compounds as PHD Inhibitors for Treating Heart, Lung, Liver, and Kidney Diseases. ACS Med Chem Lett. 2021;12(12):1868-1869. Published 2021 Nov 4. DOI:10.1021/acsmedchemlett.1c00570 |
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