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2714560-39-9

2714560-39-9 Structure

2714560-39-9 Structure
IdentificationBack Directory
[Name]

CG428-NEG
[CAS]

2714560-39-9
[Synonyms]

CG428-NEG
Hazard InformationBack Directory
[Uses]

CG428-NEG is a TRK degrader negative control. CG428 (HY-137465) inhibits cell growth and reduce TPM3-TRKA levels[1].
[References]

[1] Chen L, et al. Discovery of First-In-Class Potent and Selective Tropomyosin Receptor Kinase Degraders. J Med Chem. 2020 Dec 10;63(23):14562-14575. DOI:10.1021/acs.jmedchem.0c01342
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