| Identification | Back Directory | [Name]
arisostatin A | [CAS]
271574-41-5 | [Synonyms]
arisostatin A
18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-15-carboxaldehyde, 1,2,3,4,4a,6a,9,10,12a,13,16,20,20a,20b-tetradecahydro-13,21-dihydroxy-1,3,7,11,20a-pentamethyl-18,20-dioxo-10-[[2,3,4,6-tetradeoxy-4-[(methoxycarbonyl)amino]-3-C-methyl-3-nitro-β-D-xylo-hexopyranosyl]oxy]-4-[(O-2,3,6... | [Molecular Formula]
C69H100N2O24 | [MOL File]
271574-41-5.mol | [Molecular Weight]
1341.55 |
| Hazard Information | Back Directory | [Uses]
Arisostatin A, a microbial secondary metabolite, is an antibiotic against Gram-positive bacteria and shown to possess potent anti-tumor properties. Arisostatin A induces apoptosis through the activation of caspase-3 and reactive oxygen species (ROS) generation in AMC-HN-4 cells[1]. | [References]
[1] Kim YH, et al. Arisostatins A induces apoptosis through the activation of caspase-3 and reactive oxygen species generation in AMC-HN-4 cells. Biochem Biophys Res Commun. 2003 Sep 19;309(2):449-56. DOI:10.1016/j.bbrc.2003.07.009 |
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