| Identification | Back Directory | [Name]
3-METHYLQUINOLIN-2-ONE | [CAS]
2721-59-7 | [Synonyms]
3-methylcarbostyril
3-METHYLQUINOLIN-2-ONE
3-Methyl-2-quinolinone
3-methyl-3H-quinolin-2-one
3-Methyl-2(1H)-quinolinone
3-methyl-1H-quinolin-2-one
3-Methylquinolin-2(1H)-one
2(1H)-Quinolinone, 3-methyl-
3-methyl-1,2-dihydroquinolin-2-one
3-Methyl-1,2-dihydroquinoline-2-one
3 methyl 1,2 dihydroquinolin 2 one,3methyl1,2dihydroquinolin2one | [Molecular Formula]
C10H9NO | [MDL Number]
MFCD08705733 | [MOL File]
2721-59-7.mol | [Molecular Weight]
159.18 |
| Chemical Properties | Back Directory | [Melting point ]
234-235 °C | [Boiling point ]
346.0±35.0 °C(Predicted) | [density ]
1.136±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
11.84±0.70(Predicted) | [LogP]
1.850 (est) |
| Hazard Information | Back Directory | [Uses]
3-Methylcarbostyril (compound 5) is a BRD4 BD1 inhibitor with a pIC50 of 4.4[1]. | [Definition]
ChEBI: 3-Methyl-quinolin-2-ol is a quinolone. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 38, p. 3740, 1973 DOI: 10.1021/jo00961a019 | [IC 50]
BRD4 BD1: 4.4 (pIC50) | [References]
[1] Emmanuel H Demont, et al. Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors. J Med Chem. 2015 Jul 23;58(14):5649-73. DOI:10.1021/acs.jmedchem.5b00772 |
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