| Identification | Back Directory | [Name]
1,2,5-Oxadiazole-3-carboxamide, N-[(S)-[6-[(1S)-1-(6-cyano-1,2,4-triazolo[4,3-a]pyridin-3-yl)-3,3,3-trifluoropropyl]-7-fluoro-1H-benzimidazol-2-yl](4,4-difluorocyclohexyl)methyl]-4-methyl- | [CAS]
2724206-27-1 | [Synonyms]
IL-17 modulator 5
1,2,5-Oxadiazole-3-carboxamide, N-[(S)-[6-[(1S)-1-(6-cyano-1,2,4-triazolo[4,3-a]pyridin-3-yl)-3,3,3-trifluoropropyl]-7-fluoro-1H-benzimidazol-2-yl](4,4-difluorocyclohexyl)methyl]-4-methyl- | [Molecular Formula]
C28H23F6N9O2 | [MOL File]
2724206-27-1.mol | [Molecular Weight]
631.53 |
| Hazard Information | Back Directory | [Uses]
IL-17 modulator 5 (compound 26) is a IL-17 inhibitor, with an IC50 of 1 nM[1]. | [References]
[1] Ram W Sabnis, et al. Novel Difluorocyclohexyl Derivatives as IL-17 Modulators for Treating Inflammatory and Autoimmune Diseases. ACS Med Chem Lett. 2021 Nov 18;12(12):1883-1884. DOI:10.1021/acsmedchemlett.1c00608 |
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