| Identification | Back Directory | [Name]
[1,1'-Biphenyl]-4-carboxamide, N-[4-[(3aR,9bS)-8-cyano-1,3a,4,9b-tetrahydro[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl]butyl]- | [CAS]
273203-30-8 | [Synonyms]
S33084
S-33084
S 33084
[1,1'-Biphenyl]-4-carboxamide, N-[4-[(3aR,9bS)-8-cyano-1,3a,4,9b-tetrahydro[1]benzopyrano[3,4-c]pyrrol-2(3H)-yl]butyl]- | [Molecular Formula]
C29H29N3O2 | [MDL Number]
MFCD03792763 | [MOL File]
273203-30-8.mol | [Molecular Weight]
451.56 |
| Hazard Information | Back Directory | [Description]
S33084 is a novel, potent, selective, and competitive antagonist at dopamine D(3)-receptors. | [Uses]
S33084 is a dopamine D(3)-receptor antagonist with the pKi values of 8.72, 8.62 and 6.82 of cloned rat dopamine D3 receptor, native rat dopamine D3 and D2 receptor[1]. | [References]
[1] Cussac D, et al. The novel antagonist, S33084, and GR218,231 interact selectively with cloned and native, rat dopamine D(3) receptors as compared with native, rat dopamine D(2) receptors. Eur J Pharmacol. 2000;394(1):47-50. DOI:10.1016/s0014-2999(00)00149-7 |
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