| Identification | Back Directory | [Name]
3-Azabicyclo[3.1.0]hexane-3-carboxylicacid,6-amino-,1,1-dimethylethylester, | [CAS]
273206-92-1 | [Synonyms]
exo-6-Amino-3-Boc-3-azabi...
exo-6-Amino-3-Boc-3-azabicyclo[3.1.0]hexane
(1alpha,5alpha,6alpha)-6-Amino-3-Boc-3-azabicyclo[3.1.0]hexane
tert-butyl (exo-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
trans-tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
(1R,5S,6s)-tert-butyl 6-aMino-3-azabicyclo[3.1.0]hexane-3-carbox
tert-butyl (1S,5R)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
6-AMino-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester
(1R,5S,6s)-tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
rac(1R,5S,6S)-tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
tert-Butyl rel-(1R,5S,6S)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
exo-6-Amino-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester
rel-(1R,5S,6s)-tert-Butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
Meso-(1R,5S,6s)-tert-Butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
(+/-)-(1R,5S,6S)-tert-Butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
(1α,5α,6α)-6-AMino-3-azabicyclo[3.1.0]hexane-3-carboxylic Acid 1,1-DiMethylethyl Ester
3-Azabicyclo[3.1.0]hexane-3-carboxylic acid, 6-amino-, 1,1-dimethylethyl ester, (1α,5α,6α)-
tert-Butyl rel-(1R,5S,?6S)?-?6-?amino-?3-?azabicyclo[3.1.0]?hexane-?3-?carboxylate 273206-92-1
3-Azabicyclo[3.1.0]hexane-3-carboxylic acid, 6-amino-, 1,1-dimethylethyl ester, (1alpha,5alpha,6alpha)- | [Molecular Formula]
C10H18N2O2 | [MDL Number]
MFCD15111971 | [MOL File]
273206-92-1.mol | [Molecular Weight]
198.27 |
| Chemical Properties | Back Directory | [Melting point ]
45-47° | [Boiling point ]
275℃ | [density ]
1.144 | [Fp ]
120℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
8.52±0.20(Predicted) | [Appearance]
Off-white to yellow Solid | [InChI]
InChI=1/C10H18N2O2/c1-10(2,3)14-9(13)12-4-6-7(5-12)8(6)11/h6-8H,4-5,11H2,1-3H3/t6-,7+,8+ | [InChIKey]
UWWZMHWHRBGMIT-JIGDXULJNA-N | [SMILES]
N[C@@H]1[C@@]2([H])CN(C(=O)OC(C)(C)C)C[C@@]12[H] |&1:1,2,14,r| |
| Hazard Information | Back Directory | [Uses]
(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hexane-3-carboxylic Acid 1,1-Dimethylethyl Ester, is an intermediate in the preparation of a novel series of Histone Deacetylase (HDAC) Inhibitors, demonstrating class I selectivity and good oral bioavailability. It can also be used in the synthesis of Alatrofloxacin Mesylate (A511400). | [Synthesis]
Tert-butyl REL-(1R,5S,6S)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate was prepared by using tert-butyl chloroformate and 3-azabicyclo[3.1.0]hexan-6-amine as starting materials. Take a dry three-necked reaction flask, one fitted with a calcium chlor |
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