ChemicalBook--->CAS DataBase List--->27321-96-6

27321-96-6

27321-96-6 Structure

27321-96-6 Structure
IdentificationBack Directory
[Name]

CHOLETH-10
[CAS]

27321-96-6
[Synonyms]

CHOLETH
CHOLETH-10
CHOLETH-20
CHOLETH-24
Chol-PEG600
POLYOXYETHYLENE24CHOLESTEROLETHER
POLYOXYETHYLENE32CHOLESTERYLETHER
polyoxyethylene-24-cholesteryl ether
Polyethyleneglycol cholesteryl ether
5-Cholestene-3.beta.-polyethyleneoxide
polyethylene glycol monocholesteryl ether
glycols, polyethylene, monocholesteryl ether
Poly(oxy-1,2-ethanediyl),a-(3b)-cholest-5-en-3-yl-w-hydroxy-
Poly(oxy-1,2-ethanediyl), .alpha.-(3.beta.)-cholest-5-en-3-yl-.omega.-hydroxy-
2-[[10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]ethanol
2-[[(3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13- dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[ a]phenanthren-3-yl]oxy]ethanol
[Molecular Formula]

C29H50O2
[MOL File]

27321-96-6.mol
[Molecular Weight]

430.706
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

methylene chloride solution
[Cosmetics Ingredients Functions]

SURFACTANT - CLEANSING
SURFACTANT - EMULSIFYING
[LogP]

9.798 (est)
[EPA Substance Registry System]

Poly(oxy-1,2-ethanediyl), .alpha.-(3.beta.)-cholest-5-en-3-yl-.omega.-hydroxy- (27321-96-6)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[TSCA ]

TSCA listed
Hazard InformationBack Directory
[Uses]

Chol-PEG is a nonionic surfactant vesicles and can be used for a blood-persistent drug delivery system[1][2].
[Biological Activity]

PEG-cholesterol is widely used for cationic DNA transfection studiesand preparation of liposomes for encapsulated drug delivery.
[References]

[1] Yang DB, et, al. Synthesis and application of poly(ethylene glycol)-cholesterol (Chol-PEGm) conjugates in physicochemical characterization of nonionic surfactant vesicles. Colloids Surf B Biointerfaces. 2008 Jun 1;63(2):192-9. DOI:10.1016/j.colsurfb.2007.11.019
[2] Barnard A, et, al. Effects of a PEG additive on the biomolecular interactions of self-assembled dendron nanostructures. Org Biomol Chem. 2012 Nov 14;10(42):8403-9. DOI:10.1039/c2ob26584b
27321-96-6 suppliers list
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