| Identification | Back Directory | [Name]
(2S)-2-[[4-Amino-5-(4-methoxybenzoyl)-2-thiazolyl](4-fluorophenyl)amino]propanamide | [CAS]
2732902-09-7 | [Synonyms]
(S)-2-((4-amino-5-(4-methoxybenzoyl)thiazol-2-yl)(4-fluorophenyl)amino)propanamide
(2S)-2-[[4-Amino-5-(4-methoxybenzoyl)-2-thiazolyl](4-fluorophenyl)amino]propanamide | [Molecular Formula]
C20H19FN4O3S | [MOL File]
2732902-09-7.mol | [Molecular Weight]
414.46 |
| Chemical Properties | Back Directory | [Boiling point ]
681.7±65.0 °C(Predicted) | [density ]
1.383±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
15.27±0.50(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
(S)-BAY 2965501 is the left-handed isomer of BAY 2965501 (HY-153343). BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer[1]. | [References]
[1] Schubert N, et al. Phosphorylated extracellular signal-regulated kinase (pERK) activation in T effector cells as a target engagement biomarker for the DGK味 inhibitor BAY2965501 in clinical trials. Cancer Research, 2023, 83(7_Supplement): 2116-2116. |
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ChemShuttle, Inc.
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www.jiehuapharma.com/ |
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