| Identification | Back Directory | [Name]
3-(1-(naphthalen-2-ylmethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine | [CAS]
2734916-64-2 | [Synonyms]
ERK5-IN-6
3-(1-(naphthalen-2-ylmethyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine | [Molecular Formula]
C23H21N3 | [MOL File]
2734916-64-2.mol | [Molecular Weight]
339.43 |
| Hazard Information | Back Directory | [Uses]
ERK5-IN-6 (compound 5J) is an ERK5 kinase inhibitor with anticancer activity. ERK5-IN-6 exhibits good anti-proliferative activity with the IC50 value of 4.56 μg/mL for A549 cells[1]. | [IC 50]
ERK | [References]
[1] Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503. DOI:10.1016/j.bmc.2023.117503 |
|
|