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2734918-33-1

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2734918-33-1 Structure

2734918-33-1 Structure
IdentificationBack Directory
[Name]

JAK1/TYK2-IN-4
[CAS]

2734918-33-1
[Synonyms]

JAK1/TYK2-IN-4
[Molecular Formula]

C17H23N7O
[MOL File]

2734918-33-1.mol
[Molecular Weight]

341.41
Chemical PropertiesBack Directory
[density ]

1.43±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

15.84±0.20(predicted)
Hazard InformationBack Directory
[Uses]

JAK1/TYK2-IN-4 is a dual inhibitor of JAK and TYK2, with IC50s of 39 nM and 21 nM, respectively. JAK1/TYK2-IN-4 has oral bioavailability[1].
[References]

[1] Xue Cui, et al. Therapeutic potential of a synthetic dual JAK1/TYK2 inhibitor in inflammatory bowel disease. Int Immunopharmacol. 2023 Nov 20:126:111238. DOI:10.1016/j.intimp.2023.111238
2734918-33-1 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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