| Identification | Back Directory | [Name]
1H-Isoindole-1-carboxamide, 2-acetyl-N-[2'-fluoro-4'-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1'-biphenyl]-4-yl]-2,3-dihydro-5-(methylsulfonyl)-, (1R)- | [CAS]
2738333-10-1 | [Synonyms]
RORγt inverse agonist 26
1H-Isoindole-1-carboxamide, 2-acetyl-N-[2'-fluoro-4'-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1'-biphenyl]-4-yl]-2,3-dihydro-5-(methylsulfonyl)-, (1R)- | [Molecular Formula]
C27H21F7N2O5S | [MOL File]
2738333-10-1.mol | [Molecular Weight]
618.52 |
| Hazard Information | Back Directory | [Uses]
RORγt inverse agonist 26 is a potent reverse agonist of RORγt. RORγt inverse agonist 26 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 26 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 1) [1]. | [References]
[1] Yaobang Chen, et al. Biaryls as RORγ Modulators. Patent WO2021228215A1. |
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Biorbyt Ltd.
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+44 (0)1223 859 353 |
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http://www.biorbyt.com |
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