| Identification | Back Directory | [Name]
Imidazo[1,2-a]pyridine | [CAS]
274-76-0 | [Synonyms]
Pyrimidazole
1-Azaindolizine
1,3a-Diazaindene
IMIDAZO[1,2-A]PYRIDINE
IMidazo[1,2-a]pyridine 99%
Pyridino[1',2':1,2]glyoxaline | [Molecular Formula]
C7H6N2 | [MDL Number]
MFCD00005553 | [MOL File]
274-76-0.mol | [Molecular Weight]
118.14 |
| Chemical Properties | Back Directory | [Boiling point ]
103 °C1 mm Hg(lit.)
| [density ]
1.165 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.626(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform, Methanol | [form ]
Powder | [pka]
6.80±0.30(Predicted) | [color ]
White to off-white | [λmax]
297nm(EtOH)(lit.) | [InChI]
1S/C7H6N2/c1-2-5-9-6-4-8-7(9)3-1/h1-6H | [InChIKey]
UTCSSFWDNNEEBH-UHFFFAOYSA-N | [SMILES]
c1ccn2ccnc2c1 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow to Brown Oil | [Uses]
Imidazo[1,2-a]pyridine is one of four imidazopyridine isomers. Imidazopyridine derivatives possess activity as inhibitors of target enzymes and have medicinal and pharmaceutical applications and are u
sed as herbicides and fungicides. | [General Description]
In vivo anti-trypanosomal activity of imidazo[1,2-a]pyridiness in the STIB900 mouse model has been investigated. | [Purification Methods]
1-Azaindolizine is purified by distillation or gas chromatography. [Bower & Ramage J Chem Soc 4506 1957, Armarego J Chem Soc 4226 1964, Beilstein 23 II 1554, 23 III/IV 1104.] |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-37/39 | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29339900 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Questions And Answer | Back Directory | [Synthesis review]
A mild, catalytic, atom economical synthesis of imidazo[1,2-a]pyridines has been developed: catalytic PicAuCl2 in the presence of an acid produces a range imidazo[1,2-a]pyridines in good yield.
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