| Identification | Back Directory | [Name]
Methanone, [(2R)-2-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-1-pyrrolidinyl][2-(methylthio)phenyl]- | [CAS]
2743432-99-5 | [Synonyms]
POP-IN-1
Methanone, [(2R)-2-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-1-pyrrolidinyl][2-(methylthio)phenyl]- | [Molecular Formula]
C22H30BNO3S | [MOL File]
2743432-99-5.mol | [Molecular Weight]
399.35 |
| Hazard Information | Back Directory | [Uses]
POP-IN-1 (Compound 12h) is a potent inhibitor of POP with an Ki of 0.009 μM. POP-IN-1 has the potential for the research of neurodegenerative diseases and cancer progression[1]. | [References]
[1] Plescia J, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783. DOI:10.1016/j.ejmech.2019.111783 |
|
|