ChemicalBook--->CAS DataBase List--->2748394-67-2

2748394-67-2

2748394-67-2 Structure

2748394-67-2 Structure
IdentificationBack Directory
[Name]

DBCO-PEG3-oxyamine
[CAS]

2748394-67-2
[Synonyms]

DBCO-PEG3-oxyamine
[Molecular Formula]

C29H36N4O7
[MOL File]

2748394-67-2.mol
[Molecular Weight]

552.62
Chemical PropertiesBack Directory
[Boiling point ]

906.9±65.0 °C(predicted)
[density ]

1.28±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Oil
[pka]

14.92±0.46(predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

DBCO-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-oxyamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
[IC 50]

Non-cleavable Linker
[References]

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
2748394-67-2 suppliers list
Company Name: Zhengzhou Acme Chemical Co., Ltd.  
Telephone: 037163312495 13303845143
Website: www.acmechem.cn
Company Name: Nanchang Tianzhen Biotechnology Co., Ltd  
Telephone: 13758194781 13173652190
Website: www.tanzhenbio.com
Company Name: Shanghai Haohong Pharmaceutical Co., Ltd.  
Telephone: 400-8210725 4008210725
Website: https://www.leyan.com/
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  
Telephone: 17634413542
Website: www.mengtaichem.com
Company Name: YantaiBio  
Telephone: 13758194781; 13758194781
Website:
Company Name: Fuan Bio  
Telephone: 15002819872
Website: fuanbio.com
Tags:2748394-67-2 Related Product Information
166388-57-4 170908-81-3 1384870-47-6 1006711-90-5 68181-17-9 67605-85-0