| Identification | Back Directory | [Name]
Rubiginone D2 | [CAS]
274913-71-2 | [Synonyms]
Rubiginone D2
(2S,3S,4R)-3,4-Dihydro-2,4-dihydroxy-8-methoxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione
Benz[a]anthracene-1,7,12(2H)-trione, 3,4-dihydro-2,4-dihydroxy-8-methoxy-3-methyl-, (2S,3S,4R)- | [Molecular Formula]
C20H16O6 | [MDL Number]
MFCD28898427 | [MOL File]
274913-71-2.mol | [Molecular Weight]
352.34 |
| Chemical Properties | Back Directory | [Boiling point ]
639.5±55.0 °C(Predicted) | [density ]
1.465±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
A solid | [pka]
12.58±0.60(Predicted) | [color ]
Yellow solid with a green cast |
| Hazard Information | Back Directory | [Uses]
Rubiginone D2 is an antibiotic, which exhibits antimicrobial activities against Bacillus subtilis, Staphylococcus aureus and Escherichia coli. Rubiginone D2 exhibits antitumor efficacy, inhibits proliferations of cancer cells HM02, Kato III, HepG2 and MCF7, with GI50s of 0.1, 0.7, <0.1 and 7.5 μM, respectively[1]. | [storage]
+4°C | [References]
[1] Puder C, et al., New biologically active rubiginones from Streptomyces sp. J Antibiot (Tokyo). 2000 Apr;53(4):329-36. DOI:10.7164/antibiotics.53.329 |
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