| Identification | Back Directory | [Name]
2,6-Piperidinedione, 3-(6-fluoro-1-oxo-2(1H)-phthalazinyl)- | [CAS]
2753651-18-0 | [Synonyms]
E3 ligase Ligand 42 2,6-Piperidinedione, 3-(6-fluoro-1-oxo-2(1H)-phthalazinyl)- | [Molecular Formula]
C13H10FN3O3 | [MOL File]
2753651-18-0.mol | [Molecular Weight]
275.24 |
| Hazard Information | Back Directory | [Uses]
E3 ligase Ligand 42 is an E3 ubiquitin ligase ligand. E3 ligase Ligand 42 can be connected to the target protein ligand through a linker and can be used to synthesize PROTAC AR Degrader-6 (HY-156751). PROTAC can induce ubiquitination degradation of cancer-promoting proteins[1]. | [IC 50]
Cereblon | [References]
[1] Hongfu Lu, et al. Phthalazinone compound, and preparation method therefor and medical use thereof. WO2021249534A1. 2021-06-11 |
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