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27570-21-4

27570-21-4 Structure

27570-21-4 Structure
IdentificationBack Directory
[Name]

3-Acetyl Betulinaldehyde
[CAS]

27570-21-4
[Synonyms]

3-Acetyl Betulinaldehyde
[Molecular Formula]

C32H50O3
[MOL File]

27570-21-4.mol
[Molecular Weight]

482.75
Chemical PropertiesBack Directory
[Melting point ]

199-200 °C(Solv: ethyl ether (60-29-7); methanol (67-56-1))
[Boiling point ]

527.0±33.0 °C(Predicted)
[density ]

1.05±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Chloroform: 10 mg/ml,DMF: 1 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Uses]

3-O-Acetylbetulin aldehyde is a derivative of Betulin (HY-N0083). 3-O-Acetylbetulin aldehyde has anticancer activity[1][2].
[Biological Activity]

3-Acetyl betulinaldehyde is a triterpene and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in A. japonica.1 It is an intermediate in the synthesis of 3-acetylbetulinic acid, as well as various lupine and germanicane triterpenes and saponins with anticancer activity.2
[storage]

-20°C
[References]

1.Tung, N.H., Kwon, H.-J., Kim, J.-H., et al.An anti-influenza component of the bark of Alnus japonicaArch. Pharm. Res.33(3)363-367(2010) 2.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007)
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