| Hazard Information | Back Directory | [Uses]
HSD17B13-IN-11 (Compound 2) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. HSD17B13-IN-11 can be used in the research of liver diseases, metabolic disorders, or cardiovascular diseases such as NAFLD or NASH, or drug-induced liver injury (DILI)[1]. | [References]
[1] Odingo J, et al. Thiophene hsd17b13 inhibitors and uses thereof. U.S., WO2022020714. 2023-09-07. |
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