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BI-10 is an antifungal compound. BI-10 combined with Fluconazole can inhibit hyphal growth, result in ROS accumulation, and decrease mitochondrial membrane potential (MMP) as well as altering membrane permeability[1]. | [References]
[1] Jiang Y, et al. Synthesis and antifungal evaluation of phenol-derived bis(indolyl)methanes combined with FLC against Candida albicans. Bioorg Med Chem Lett. 2022;58:128525. DOI:10.1016/j.bmcl.2022.128525 |
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