| Hazard Information | Back Directory | [Uses]
PIM1-IN-4 (Compound 8) is a potent inhibitor of PIM1. PIM1-IN-4 reveals strong inhibition of five other enzymes, i.e., SGK-1, PKA, CaMK-1, GSK3β, and MSK1. PIM1-IN-4 has the potential for the research of cancer diseases[1]. | [IC 50]
PIM1 | [References]
[1] Wittmann C, et al. Highly Antiproliferative Latonduine and Indolo[2,3-c]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile. J Med Chem. 2022 Feb 10;65(3):2238-2261. DOI:10.1021/acs.jmedchem.1c01740 |
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