| Identification | Back Directory | [Name]
Oleana-1,9(11)-dien-28-oic acid, 2-cyano-3,12-dioxo-, 4-[(4-hydroxybenzoyl)oxy]butyl ester | [CAS]
2763063-15-4 | [Synonyms]
Oleana-1,9(11)-dien-28-oic acid, 2-cyano-3,12-dioxo-, 4-[(4-hydroxybenzoyl)oxy]butyl ester | [Molecular Formula]
C42H53NO7 | [MOL File]
2763063-15-4.mol | [Molecular Weight]
683.87 |
| Hazard Information | Back Directory | [Uses]
Apoptosis inducer 25 (Compound 4H) inhibits the proliferation of cell BGC-823 with IC50 of 0.37 μM. Apoptosis inducer 25 arrests cell cycle at G2/M phase, induces apoptosis in cell BGC-823, and causes mitochondrial dysfunction. Apoptosis inducer 25 exhibits good pharmacokinetic properties in rats[1]. | [References]
[1] Li N, et al., New CDDO Arylboronate Ester Derivatives with High Selectivity and Low Toxicity. J Med Chem. 2024 Aug 22;67(16):14329-14344. DOI:10.1021/acs.jmedchem.4c01160 |
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