ChemicalBook--->CAS DataBase List--->2765319-65-9

2765319-65-9

2765319-65-9 Structure

2765319-65-9 Structure
IdentificationBack Directory
[Name]

VJDT
[CAS]

2765319-65-9
[Synonyms]

VJDT
[Molecular Formula]

C23H17N3O3
[MOL File]

2765319-65-9.mol
[Molecular Weight]

383.4
Chemical PropertiesBack Directory
[Boiling point ]

730.9±60.0 °C(predicted)
[density ]

1.44±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

-3.13±0.40(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

VJDT is a TREM1 small molecule inhibitor that effectively blocks TREM1 signaling. VJDT inhibits tumor growth and can be used in cancer research[1].
[References]

[1] Ajith A,et al. Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance. J Clin Invest. 2023 Nov 1;133(21):e167951. DOI:10.1172/JCI167951
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