| Identification | Back Directory | [Name]
2-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-6-[(4-methylphenyl)methylene]-5-oxo-, (6E)- | [CAS]
2765796-41-4 | [Synonyms]
Firefly luciferase-IN-1
(E)-6-(4-methylbenzylidene)-5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid
2-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-6-[(4-methylphenyl)methylene]-5-oxo-, (6E)-
(E)6(4methylbenzylidene)5oxo5,6,7,8tetrahydronaphthalene2carboxylic acid,(E) 6 (4 methylbenzylidene) 5 oxo 5,6,7,8 tetrahydronaphthalene 2 carboxylic acid | [Molecular Formula]
C19H16O3 | [MOL File]
2765796-41-4.mol | [Molecular Weight]
292.33 |
| Chemical Properties | Back Directory | [Boiling point ]
524.0±50.0 °C(Predicted) | [density ]
1.274±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.83±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Firefly luciferase-IN-1 (compound 48) is a highly potent and reversible inhibitor of firefly luciferase with an IC50 value of 0.25 nM[1]. | [References]
[1] Li Y, et al. Identification of 2-Benzylidene-tetralone Derivatives as Highly Potent and Reversible Firefly Luciferase Inhibitors. ACS Med Chem Lett. 2022 Jan 20;13(2):304-311. DOI:10.1021/acsmedchemlett.1c00671 |
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