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Aβ-IN-1 is a Aβ1-42 aggregation inhibitor. Aβ-IN-1 inhibits Aβ1-42 self-aggregation in vitro by delaying the exponential growth phase or reduces the quantity of fibrils in the steady state. Aβ-IN-1 can be used for the research of conformational disorders[1]. | [References]
[1] Hélio M T Albuquerque, et al. Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes. ACS Med Chem Lett. 2022 Feb 14;13(3):443-448. DOI:10.1021/acsmedchemlett.1c00604 |
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