2769141-82-2

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2769141-82-2 Structure

Chemical Properties	Back Directory
[density ] 1.56±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[form ] Solid
[pka] 7.13±0.50(Predicted)
[color ] White to off-white

Hazard Information	Back Directory
[Uses] SR-1114 is a first-in-class PROTAC ENL degrader. SR-1114 elicits rapid, CRBN-dependent degradation of ENL with DC50s of 150 nM, 311 nM, and 1.65 μM in MV4;11 , MOLM-13, and OCI/AML-2 cells, respectively[1].
[IC 50] Cereblon
[References] [1] Leopold Garnar-Wortzel,?et al. Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia. ACS Cent Sci.?2021 May 26;7(5):815-830. DOI:10.1021/acscentsci.0c01550

2769141-82-2 suppliers list

Company Name:	Nantong QuanYi Biotechnology Co., Ltd
Tel:	0513-66337626 18051384581
Website:	https://www.chemhifuture.com/

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