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MAGL-IN-14 (compound 2) is a potent inhibitor of MAGL, with IC50 of 0.00289 μM and 0.002 μM in HEK293 and PC3 cells, respectively[1]. | [References]
[1] H. Lundbeck A/S. Preparation of ubstituted 1,1,1,3,3,3-hexafluoropropan-2-yl 6-azaspiro[2.5]octane-6-carboxylates as MAGL inhibitors. World Intellectual Property Organization, WO2022101412 A1 2022-05-19. |
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