| Identification | Back Directory | [Name]
2,4-Pyrimidinediamine, N2-[3-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- | [CAS]
2785430-85-3 | [Synonyms]
ALK5-IN-29
2,4-Pyrimidinediamine, N2-[3-fluoro-5-(1-piperazinylmethyl)phenyl]-N4-(8-methyl-4-cinnolinyl)- | [Molecular Formula]
C24H25FN8 | [MOL File]
2785430-85-3.mol | [Molecular Weight]
444.51 |
| Hazard Information | Back Directory | [Uses]
ALK5-IN-29 is an selective activin receptor-like kinase (ALK) inhibitor. ALK5-IN-29 can inhibit the activity of ALK5 with an IC50 value of ≤10 nM. ALK5-IN-29 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer[1]. | [References]
[1] Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent. WO2022126133A1. |
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