| Identification | Back Directory | [Name]
DIBENZOFURAN-4-CARBOXYLIC ACID | [CAS]
2786-05-2 | [Synonyms]
4-Dibenzofurancarboxylic acid
DIBENZOFURAN-4-CARBOXYLIC ACID
Dibenzofuran-4-carboxylic acid 97%
dibenzo[b,d]furan-4-carboxylic acid
8-oxatricyclo[7.4.0.0,2,7]trideca-1(9),2,4,6,10,12-he
xaene-6-carboxylic acid | [Molecular Formula]
C13H8O3 | [MDL Number]
MFCD00092335 | [MOL File]
2786-05-2.mol | [Molecular Weight]
212.2 |
| Chemical Properties | Back Directory | [Melting point ]
211-215 °C(lit.)
| [Boiling point ]
425.7±18.0 °C(Predicted) | [density ]
1.387±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 1 mg/ml | [form ]
solid | [pka]
3.24±0.30(Predicted) | [color ]
White to light yellow | [InChI]
InChI=1S/C13H8O3/c14-13(15)10-6-3-5-9-8-4-1-2-7-11(8)16-12(9)10/h1-7H,(H,14,15) | [InChIKey]
BSMAWCXKHJSJIB-UHFFFAOYSA-N | [SMILES]
O1C2=CC=CC=C2C2=CC=CC(C(O)=O)=C12 |
| Hazard Information | Back Directory | [Uses]
4-Dibenzofurancarboxylic acid is one of the synthesis materials of polycyclic aromatic hydrocarbons (PAHs) and Schistosoma mansoni histone deacetylase 8 (smHDAC8) inhibitors[1][2]. | [References]
[1] Ghazy E, et al. Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis. Eur J Med Chem. 2021 Dec 5;225:113745. DOI:10.1016/j.ejmech.2021.113745
[2] Molotkov AP, et al. Effect of Cp-Ligand Methylation on Rhodium(III)-Catalyzed Annulations of Aromatic Carboxylic Acids with Alkynes: Synthesis of Isocoumarins and PAHs for Organic Light-Emitting Devices. Chempluschem. 2020 Feb;85(2):334-345. DOI:10.1002/cplu.202000048 |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|