| Hazard Information | Back Directory | [Uses]
Rha-PEG3-SMCC (compound 13) is a agent-linker conjugate for ADC with potent antitumor activity by using SMCC (a protein crosslinker), linked via the noncleavable ADC linker Rha-PEG3. | [IC 50]
Traditional Cytotoxic Agents | [References]
[1] Kun Zhou, et al. Chemical Synthesis of Antibody-Hapten Conjugates Capable of Recruiting the Endogenous Antibody to Magnify the Fc Effector Immunity of Antibody for Cancer Immunotherapy. J Med Chem. 2022 Jan 13;65(1):323-332. DOI:10.1021/acs.jmedchem.1c01480 |
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