| Identification | Back Directory | [Name]
2-Propenamide, 2-cyano-3-(1,2-dihydro-2-oxo-3-quinolinyl)-N-(4-hydroxyphenyl)- | [CAS]
2803505-57-7 | [Synonyms]
Pim-1 kinase inhibitor 1
2-Propenamide, 2-cyano-3-(1,2-dihydro-2-oxo-3-quinolinyl)-N-(4-hydroxyphenyl)- | [Molecular Formula]
C19H13N3O3 | [MOL File]
2803505-57-7.mol | [Molecular Weight]
331.32 |
| Hazard Information | Back Directory | [Uses]
Pim-1 kinase inhibitor 1 is a Pim-1 kinase inhibitor with an IC50 of 0.11 μM for Pim-1 kinase. Pim-1 kinase inhibitor 1 shows anticancer activity to several cancer cell lines by promotes cell apoptosis. Pim-1 kinase inhibitor 1 can be used for the research of cancer[1]. | [References]
[1] A. Ammar, et al. Carboxamide appended quinoline moieties as potential anti-proliferative agents, apoptotic inducers and Pim-1 kinase inhibitors. 2021. |
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