| Identification | Back Directory | [Name]
2-METHYLIMIDAZO[1,2-A]PYRIDIN-3-AMINE | [CAS]
28036-31-9 | [Synonyms]
2-METHYLIMIDAZO[1,2-A]PYRIDIN-3-AMINE
3-Amino-2-methylimidazo[1,2-a]pyridine
Imidazo[1,2-a]pyridin-3-amine, 2-methyl- | [Molecular Formula]
C8H9N3 | [MDL Number]
MFCD09800571 | [MOL File]
28036-31-9.mol | [Molecular Weight]
147.18 |
| Chemical Properties | Back Directory | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
crystalline solid | [pka]
9.08±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Synthesis]
General procedure: Preparation of Example 14
2-Methyl-3-nitroimidazo[1,2-a]pyridine (330.0 mg, 1.86 mmol) was dissolved in 8 mL of ethanol. 10% palladium-carbon catalyst (20 mg, 0.2 mmol) was added to the solution under argon protection. The reaction mixture was stirred under hydrogen atmosphere for 18 hours. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to afford 2-methylimidazo[1,2-a]pyridin-3-amine (260 mg, 1.76 mmol, 95% yield) as a brown solid.LRMS (m/z): 148 (M + 1)+. | [References]
[1] Patent: EP2848615, 2015, A1. Location in patent: Paragraph 0100
[2] Chemical and Pharmaceutical Bulletin, 2001, vol. 49, # 12, p. 1631 - 1635 |
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| Company Name: |
J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
| Company Name: |
Bide Pharmatech Ltd.
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400-1647117 13681763483 |
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https://www.bidepharm.com/ |
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