| Identification | Back Directory | [Name]
4(1H)-Quinazolinone, 5-chloro-2,3-dihydro-2-phenyl- | [CAS]
2819989-58-5 | [Synonyms]
PBRM1-BD2-IN-3
4(1H)-Quinazolinone, 5-chloro-2,3-dihydro-2-phenyl- | [Molecular Formula]
C14H11ClN2O | [MOL File]
2819989-58-5.mol | [Molecular Weight]
258.7 |
| Hazard Information | Back Directory | [Uses]
PBRM1-BD2-IN-3 (compound 12) is a potent PBRM1-BD2 inhibitor with an IC50 value of 1.1 μM. PBRM1-BD2 Inhibitor can be used to research anticancer[1]. | [References]
[1] Shishodia S, et al. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. J Med Chem. 2022 Oct 13. DOI:10.1021/acs.jmedchem.2c00864 |
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