| Identification | Back Directory | [Name]
Aureothin | [CAS]
2825-00-5 | [Synonyms]
Aureothin
Mycolutein
(+)-(R)-Aureothin
Strain 58 substance
Distacin, Mycolutein, 74A'', JA 2814K
2-[(2R)-4-[(1Z,2E)-2-Methyl-3-(4-nitrophenyl)-2-propenylidene]tetrahydrofuran-2-yl]-3,5-dimethyl-6-methoxy-4H-pyran-4-one
4H-Pyran-4-one, 2-methoxy-3,5-dimethyl-6-[(2R,4Z)-tetrahydro-4-[(2E)-2-methyl-3-(4-nitrophenyl)-2-propen-1-ylidene]-2-furanyl]- | [Molecular Formula]
C22H23NO6 | [MDL Number]
MFCD11519458 | [MOL File]
2825-00-5.mol | [Molecular Weight]
397.42 |
| Chemical Properties | Back Directory | [Melting point ]
157-158℃ | [alpha ]
D18 +51° (chloroform) | [Boiling point ]
520.87°C (rough estimate) | [density ]
1.2976 (rough estimate) | [refractive index ]
1.5614 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble | [form ]
A solid | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. Aureothin acts by inhibiting oxidoreductase. More recently, aureothin has been shown to be a potent inhibitor of Helicobacter pylori. | [Uses]
Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumour, antimicrobial and insecticidal activities. Aureothin acts by inhibiting oxidoreductase. More recently, aureothin has been shown to be a potent inhibitor of Helicobacter pylori. | [IC 50]
HIV: 5.3 nM (IC50) | [storage]
+4°C |
|
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