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DGKα&ζ-IN-1 (Compound II) is a DGK target inhibitor. DGKα&ζ-IN-1 can enhance the function of T cells, and has a synergistic effect with PD-1, which has therapeutic effects IN both immune and tumor[1]. | [References]
[1] Tu-Sekine B, et al. DGK-θ: Structure, Enzymology, and Physiological Roles. Front Cell Dev Biol. 2016 Sep 14;4:101. DOI:10.3389/fcell.2016.00101 |
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