2833692-02-5

Directory

2833692-02-5 Structure

Chemical Properties	Back Directory
[Boiling point ] 851.7±65.0 °C(predicted)
[density ] 1.233±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 14.42±0.40(predicted)

Hazard Information	Back Directory
[Uses] MOR agonist-2 (compound 46) is a antagonist of D3R and agonist of MOR (Ki: 7.26 nM and 564 nM, respectively). MOR agonist-2 has the potential to produce analgesic effects through MOR partial agonism. MOR agonist-2 reduces opioid-misuse liability via D3R antagonism[1].
[IC 50] D₃ Receptor; μ Opioid Receptor/MOR
[References] [1] Bonifazi A, et al. Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D3 (D3R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics. J Med Chem. 2023 Aug 10;66(15):10304-10341. DOI:10.1021/acs.jmedchem.3c00417

2833692-02-5 suppliers list

Tags:2833692-02-5 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login