2839627-76-6

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2839627-76-6 Structure

Identification	Back Directory
[Name] ABCA1 inducer 1
[CAS] 2839627-76-6
[Synonyms] ABCA1 inducer 1 Benzoic acid, 3-chloro-5-[[[5-chloro-3-[[(4-ethoxy-3-methoxyphenyl)methylamino]sulfonyl]-2-thienyl]carbonyl]amino]-, ethyl ester
[Molecular Formula] C24H24Cl2N2O7S2
[MOL File] 2839627-76-6.mol
[Molecular Weight] 587.5

Chemical Properties	Back Directory
[density ] 1.439±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka] 9.486±0.70(predicted)

Hazard Information	Back Directory
[Uses] ABCA1 inducer 1 is a nonlipogenic ABCA1 inducer. ABCA1 inducer 1 increases ABCA1 expression, enhances apolipoprotein (APOE) lipidation and reverses multiple Alzheimer’s disease (AD) phenotypes, without increasing triglycerides in E3/4FAD mice that express human APOE 3/4[1].
[References] [1] Velma GR, et al. Nonlipogenic ABCA1 Inducers (NLAI) for Alzheimer's Disease Validated in a Mouse Model Expressing Human APOE3/APOE4. J Med Chem. 2024 Sep 12;67(17):15061-15079. DOI:10.1021/acs.jmedchem.4c00733

2839627-76-6 suppliers list

Company Name:	Shanghai Beckham Medical Technology Co., Ltd
Tel:	13816613772
Website:	www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm

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